Reaction Details Report a problem with these data
Target
Accessory gene regulator protein A
Ligand
BDBM50020380
Substrate
n/a
Meas. Tech.
ChEMBL_1366621 (CHEMBL3296715)
IC50
30100±n/a nM
Citation
 Figueroa, M; Jarmusch, AK; Raja, HA; El-Elimat, T; Kavanaugh, JS; Horswill, AR; Cooks, RG; Cech, NB; Oberlies, NH Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry. J Nat Prod 77:1351-8 (2014) [PubMed]  Article 
Target
Name:
Accessory gene regulator protein A
Synonyms:
AGRA_STAAU | agr | agrA
Type:
PROTEIN
Mol. Mass.:
27903.57
Organism:
Staphylococcus aureus
Description:
ChEMBL_1366621
Residue:
238
Sequence:
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIMFFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI
  
Inhibitor
Name:
BDBM50020380
Synonyms:
CHEMBL3289789
Type:
Small organic molecule
Emp. Form.:
C17H12O7
Mol. Mass.:
328.273
SMILES:
CC(=O)C(O)c1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1
Structure:
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