Reaction Details Report a problem with these data
Target
Heat shock protein HSP 90
Ligand
BDBM50423645
Substrate
n/a
Meas. Tech.
ChEMBL_1448528 (CHEMBL3379280)
IC50
414000±n/a nM
Citation
 Gavenonis, J; Jonas, NE; Kritzer, JA Potential C-terminal-domain inhibitors of heat shock protein 90 derived from a C-terminal peptide helix. Bioorg Med Chem 22:3989-93 (2014) [PubMed]  Article 
Target
Name:
Heat shock protein HSP 90
Synonyms:
Eukaryotic peptide initiation factor 2 kinase, alpha-chain-associated phosphopeptide | HSP90_RABIT
Type:
PROTEIN
Mol. Mass.:
5288.84
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_1448528
Residue:
47
Sequence:
MPEEVQTQDQPMETFAVQTFAFQAEIAQLMSLIYESLTDPSKLDSGK
  
Inhibitor
Name:
BDBM50423645
Synonyms:
Albamycin | Cathomycin | NOVOBIOCIN
Type:
Small organic molecule
Emp. Form.:
C31H36N2O11
Mol. Mass.:
612.6243
SMILES:
[#6]-[#8]-[#6@@H]1-[#6@@H](-[#8]-[#6](-[#7])=O)-[#6@H](-[#8])-[#6@@H](-[#8]-c2ccc3c(-[#8])c(-[#7]-[#6](=O)-c4ccc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c4)c(=O)oc3c2-[#6])-[#8]C1([#6])[#6]
Structure:
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