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Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50014846
Substrate
n/a
Meas. Tech.
ChEMBL_1469668 (CHEMBL3413067)
IC50
1340±n/a nM
Citation
 Wang, SF; Yin, Y; Zhang, YL; Mi, SW; Zhao, MY; Lv, PC; Wang, BZ; Zhu, HL Synthesis, biological evaluation and 3D-QSAR studies of novel 5-phenyl-1H-pyrazol cinnamamide derivatives as novel antitubulin agents. Eur J Med Chem 93:291-9 (2015) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50014846
Synonyms:
(S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide | (S)-colchicine | 7alphaH-colchicine | CHEMBL107 | COLCHICINE | N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide | colchicina | colchicinum
Type:
Small organic molecule
Emp. Form.:
C22H25NO6
Mol. Mass.:
399.437
SMILES:
COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r|
Structure:
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