Target
Macrophage migration inhibitory factor
Ligand
BDBM50203072
Substrate
n/a
Meas. Tech.
ChEMBL_1467648 (CHEMBL3411010)
IC50
1100±n/a nM
Citation
 Spencer, ESDale, EJGommans, ALRutledge, MTVo, CTNakatani, YGamble, ABSmith, RAWilbanks, SMHampton, MBTyndall, JD Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor. Eur J Med Chem 93:501-10 (2015) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
  
Inhibitor
Name:
BDBM50203072
Synonyms:
3-isothiocyanatoprop-1-ene | Allyl isothiocyanate | Allylisothiocyanate | CHEMBL233248
Type:
Small organic molecule
Emp. Form.:
C4H5NS
Mol. Mass.:
99.154
SMILES:
C=CCN=C=S
Structure:
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