Reaction Details Report a problem with these data
Target
Transmembrane domain-containing protein TMIGD3
Ligand
BDBM50074225
Substrate
n/a
Meas. Tech.
ChEMBL_1556380 (CHEMBL3772111)
Ki
19±n/a nM
Citation
 Donegan, RK; Lieberman, RL Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions. J Med Chem 59:788-809 (2016) [PubMed]  Article 
Target
Name:
Transmembrane domain-containing protein TMIGD3
Synonyms:
TMIG3_HUMAN | TMIGD3 | Transmembrane domain-containing protein TMIGD3
Type:
PROTEIN
Mol. Mass.:
30335.79
Organism:
Homo sapiens (Human)
Description:
ChEMBL_114868
Residue:
266
Sequence:
MEGSPAGPIEQKEARWESSWEEQPDWTLGCLSPESQFRIPGLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYKNHPKYWCRGYFRDYCNIIAFSPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRDFARDDMDFTELIVTDDKGTLANDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQRNRRVGNTLKPFSRVLTPKEMAPTEQM
  
Inhibitor
Name:
BDBM50074225
Synonyms:
6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-nicotinic acid propyl ester | CHEMBL111545
Type:
Small organic molecule
Emp. Form.:
C23H29NO3S
Mol. Mass.:
399.546
SMILES:
CCCOC(=O)c1c(CCC)c(C(=O)SCC)c(CC)nc1-c1ccccc1
Structure:
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