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TargetIntestinal alkaline phosphatase
LigandBDBM50165137
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1572749
Ki 4210±n/a nM
Citation al-Rashida, MBatool, GSattar, AEjaz, SAKhan, SLecka, JSévigny, JHameed, AIqbal, J 2-Alkoxy-3-(sulfonylarylaminomethylene)-chroman-4-ones as potent and selective inhibitors of ectonucleotidases. Eur J Med Chem115:484-94 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Intestinal alkaline phosphatase
Name:Intestinal alkaline phosphatase
Synonyms:Intestinal alkaline phosphatase | Intestinal-type alkaline phosphatase (IAP)
Type:Protein
Mol. Mass.:57094.82
Organism:Bos taurus (Cattle)
Description:P19111
Residue:533
Sequence:
MQGACVLLLLGLHLQLSLGLVPVEEEDPAFWNRQAAQALDVAKKLQPIQTAAKNVILFLG
DGMGVPTVTATRILKGQMNGKLGPETPLAMDQFPYVALSKTYNVDRQVPDSAGTATAYLC
GVKGNYRTIGVSAAARYNQCKTTRGNEVTSVMNRAKKAGKSVGVVTTTRVQHASPAGAYA
HTVNRNWYSDADLPADAQMNGCQDIAAQLVNNMDIDVILGGGRKYMFPVGTPDPEYPDDA
SVNGVRKRKQNLVQAWQAKHQGAQYVWNRTALLQAADDSSVTHLMGLFEPADMKYNVQQD
HTKDPTLQEMTEVALRVVSRNPRGFYLFVEGGRIDHGHHDDKAYMALTEAGMFDNAIAKA
NELTSELDTLILVTADHSHVFSFGGYTLRGTSIFGLAPSKALDSKSYTSILYGNGPGYAL
GGGSRPDVNDSTSEDPSYQQQAAVPQASETHGGEDVAVFARGPQAHLVHGVEEETFVAHI
MAFAGCVEPYTDCNLPAPTTATSIPDAAHLAASPPPLALLAGAMLLLLAPTLY
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50165137
NameBDBM50165137
Synonyms:CHEMBL3800324
TypeSmall organic molecule
Emp. Form.C17H14Cl2N2O5S
Mol. Mass.429.274
SMILESCOC1Oc2c(Cl)cc(Cl)cc2C(=O)\C1=C/Nc1ccccc1S(N)(=O)=O
Structure
n/a