Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM50167982
Substrate
n/a
Meas. Tech.
ChEMBL_1574572 (CHEMBL3804644)
IC50
110±n/a nM
Citation
 Cisneros, JA; Robertson, MJ; Valhondo, M; Jorgensen, WL Irregularities in enzyme assays: The case of macrophage migration inhibitory factor. Bioorg Med Chem Lett 26:2764-2767 (2016) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
  
Inhibitor
Name:
BDBM50167982
Synonyms:
CHEMBL3797982
Type:
Small organic molecule
Emp. Form.:
C13H10N2O2
Mol. Mass.:
226.2307
SMILES:
Oc1ccc(cc1O)-c1cnc2ccccn12
Structure:
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