Reaction Details Report a problem with these data
Target
Cytosol aminopeptidase [33-68,L62W]
Ligand
BDBM50170884
Substrate
n/a
Meas. Tech.
ChEMBL_1577950 (CHEMBL3806574)
Ki
21100±n/a nM
Citation
 Weglarz-Tomczak, E; Berlicki, L; Pawelczak, M; Nocek, B; Joachimiak, A; Mucha, A A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases. Eur J Med Chem 117:187-96 (2016) [PubMed]  Article 
Target
Name:
Cytosol aminopeptidase [33-68,L62W]
Synonyms:
AMPL_PIG | Cytosol aminopeptidase | LAP3 | Leucine aminopeptidase (LAP)
Type:
Enzyme
Mol. Mass.:
4015.44
Organism:
Sus scrofa (Pig)
Description:
P28839[33-68,L62W]
Residue:
36
Sequence:
TKGLVLGIYSKEKEDDAPQFTSAGENFDKWVSGKLR
  
Inhibitor
Name:
BDBM50170884
Synonyms:
CHEMBL3805495
Type:
Small organic molecule
Emp. Form.:
C21H29N2O5P
Mol. Mass.:
420.4391
SMILES:
COc1ccc(CCNCC(N)P(O)(=O)CC(Cc2ccccc2)C(O)=O)cc1
Structure:
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