Reaction Details Report a problem with these data
Target
CDGSH iron-sulfur domain-containing protein 1
Ligand
BDBM50198892
Substrate
n/a
Meas. Tech.
ChEMBL_1620948 (CHEMBL3863231)
Ki
388±n/a nM
Citation
 Geldenhuys, WJ; Yonutas, HM; Morris, DL; Sullivan, PG; Darvesh, AS; Leeper, TC Identification of small molecules that bind to the mitochondrial protein mitoNEET. Bioorg Med Chem Lett 26:5350-5353 (2016) [PubMed]  Article 
Target
Name:
CDGSH iron-sulfur domain-containing protein 1
Synonyms:
C10orf70 | CISD1 | CISD1_HUMAN | MitoNEET | ZCD1
Type:
PROTEIN
Mol. Mass.:
12206.48
Organism:
Homo sapiens (Human)
Description:
ChEMBL_766432
Residue:
108
Sequence:
MSLTSSSSVRVEWIAAVTIAAGTAAIGYLAYKRFYVKDHRNKAMINLHIQKDNPKIVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKKKET
  
Inhibitor
Name:
BDBM50198892
Synonyms:
3-AP | 3-aminopyridine-2-carboxaldehyde thiosemicarbazone | Triapine | US10155732, Compound 3-AP
Type:
Small organic molecule
Emp. Form.:
C7H9N5S
Mol. Mass.:
195.245
SMILES:
NC(=S)N\N=C\c1ncccc1N
Structure:
Search PDB for entries with ligand similarity: