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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM81446
Substrate
n/a
Ki
3.4±n/a nM
Comments
PDSP_796
Citation
 Nelson, DL; Lucaites, VL; Audia, JE; Nissen, JS; Wainscott, DB Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines. J Pharmacol Exp Ther 265:1272-9 (1993) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT2 | 5HT2A_MACMU | HTR2A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52607.65
Organism:
Monkey
Description:
5-HT2 0 Monkey::P50128
Residue:
471
Sequence:
MDILCEENTSLSSTTNSLMQLNEDTRLYSNDFNSGEANTSDAFNWTVESENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHRDPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEDASKDNSDGVNEKVSCV
  
Inhibitor
Name:
BDBM81446
Synonyms:
CAS_60-79-7 | ERGONOVINE | NSC_104873
Type:
Small organic molecule
Emp. Form.:
C19H23N3O2
Mol. Mass.:
325.4048
SMILES:
CC(CO)NC(=O)C1CN(C)C2Cc3c[nH]c4cccc(C2=C1)c34 |c:22|
Structure:
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