Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50037785
Substrate
n/a
Ki
6±n/a nM
Comments
PDSP_323
Citation
 Hill, RJ; Oleynek, JJ; Hoth, CF; Kiron, MA; Weng, W; Wester, RT; Tracey, WR; Knight, DR; Buchholz, RA; Kennedy, SP Cloning, expression and pharmacological characterization of rabbit adenosine A1 and A3 receptors. J Pharmacol Exp Ther 280:122-8 (1997) [PubMed] 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RABIT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine receptor A1 (A1)
Type:
Enzyme
Mol. Mass.:
36566.33
Organism:
Oryctolagus cuniculus (Rabbit)
Description:
P34970
Residue:
328
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPETYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKAVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLREVQRAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRRQLSKKASASSGDPHKYYGKELKIAKSLALILFLFALSWLPLHILNCVTLFCPSCQKPSILVYTAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCRPAPAGDGDEDLPEEKPND
  
Inhibitor
Name:
BDBM50037785
Synonyms:
2-(6-{[2-(4-aminophenyl)ethyl]amino}-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | 2-{6-[2-(4-Amino-phenyl)-ethylamino]-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol | APNEA | CHEMBL326958 | ChEMBL_198532
Type:
Small organic molecule
Emp. Form.:
C18H22N6O4
Mol. Mass.:
386.4051
SMILES:
Nc1ccc(CCNc2ncnc3n(cnc23)C2OC(CO)C(O)C2O)cc1
Structure:
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