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Target
Glutamate receptor
Ligand
BDBM50060635
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_829
Citation
 Toms, NJ; Reid, ME; Phillips, W; Kemp, MC; Roberts, PJ A novel kainate receptor ligand [3H]-(2S,4R)-4-methylglutamate: pharmacological characterization in rabbit brain membranes. Neuropharmacology 36:1483-8 (1997) [PubMed]  Article 
Target
Name:
Glutamate receptor
Synonyms:
Glutamate kainate | Glutamate-Kainate
Type:
Enzyme Catalytic Domain
Mol. Mass.:
96238.98
Organism:
RABBIT
Description:
Glutamate-Kainate Glutamate kainate RABBIT::G1SXH9
Residue:
849
Sequence:
MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEAQWDGLTGRITFNKTDGLRKNFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTEGNKDRSNNITDSLANRTLIVTTILEEPYVMYKKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVKNNDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDVEQCLSFNAIMEELGISLKNQKKLKKKSRTKGKSSFTSILTCHQRRTQRKETVA
  
Inhibitor
Name:
BDBM50060635
Synonyms:
(S)-2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-propionic acid | (S)-2-amino-3-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid | (S)-5-Fluorowillardiine | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID | CHEMBL123132 | Fluorowillardiine
Type:
Small organic molecule
Emp. Form.:
C7H8FN3O4
Mol. Mass.:
217.1545
SMILES:
N[C@@H](Cn1cc(F)c(=O)[nH]c1=O)C(O)=O |r|
Structure:
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