Reaction Details
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Report a problem with these dataTarget
Alpha-1B adrenergic receptor
Ligand
BDBM78940
Substrate
n/a
Ki
0.50±n/a nM
Comments
PDSP_1219
Citation
Wikberg-Matsson, A; Wikberg, JE; Uhlén, S Characterization of alpha1-adrenoceptor subtypes in the pig. Eur J Pharmacol 347:301-9 (1998) [PubMed] Article More Info.:
Target
Name:
Alpha-1B adrenergic receptor
Synonyms:
ADRA1B | adrenergic Alpha1B
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34826.67
Organism:
PIG
Description:
Q70HQ0
Residue:
316
Sequence:
MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPL
Inhibitor
Name:
BDBM78940
Synonyms:
METHIOTHEPIN | MLS000859918 | Methiothepin mesylate salt | SMR000326779 | cid_3039995 | mesylic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine | methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine | methanesulfonic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine
Type:
Small organic molecule
Emp. Form.:
C20H24N2S2
Mol. Mass.:
356.548
SMILES:
CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1
Structure:
