Reaction Details
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Calcium-activated potassium channel subunit beta
Ligand
BDBM86249
Substrate
n/a
Ki
629.8±n/a nM
Comments
PDSP_3714
Citation
Davis-Taber, R; Molinari, EJ; Altenbach, RJ; Whiteaker, KL; Shieh, CC; Rotert, G; Buckner, SA; Malysz, J; Milicic, I; McDermott, JS; Gintant, GA; Coghlan, MJ; Carroll, WA; Scott, VE; Gopalakrishnan, M [125I]A-312110, a novel high-affinity 1,4-dihydropyridine ATP-sensitive K+ channel opener: characterization and pharmacology of binding. Mol Pharmacol 64:143-53 (2003) [PubMed] Article More Info.:
Target
Name:
Calcium-activated potassium channel subunit beta
Synonyms:
Potassium channel (ATP modulatory)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22836.62
Organism:
GUINEA PIG
Description:
C0KY85
Residue:
199
Sequence:
GSHAKPFMLSTQREESNCTIIHTHIMDDWMDCAFTCGVDCQGQGKYPCLQVFVNLTHSGQKALLHYNEEAVQINSKCFYTPKCRRDGNDLLNSALNIKEFFDHKNRTPFSCFYSPDNQSEDVILIKKYDQMVIFHCLFWPSMTMLGGALIVGMVRLTQYLFLLCEKYSTALRDEVSGKVPYVARNQFKLWSVGRSKGRA
Inhibitor
Name:
BDBM86249
Synonyms:
ZD 6169 | ZD-6169
Type:
Small organic molecule
Emp. Form.:
C17H14F3NO3
Mol. Mass.:
337.2932
SMILES:
C[C@](O)(C(=O)Nc1ccc(cc1)C(=O)c1ccccc1)C(F)(F)F
Structure:
