Reaction Details Report a problem with these data
Target
Phospholipase D2
Ligand
BDBM87173
Substrate
n/a
Meas. Tech.
Cellular PLD2 concentration response
IC50
250±n/a nM
Citation
 PubChem, PC Cellular PLD2 concentration response PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase D2
Synonyms:
PLD2 | PLD2_HUMAN | Phospholipase D2 | Phospholipase D2 (PLD2) | phospholipase D2 isoform PLD2A
Type:
Protein
Mol. Mass.:
106002.47
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
933
Sequence:
MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFAPGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVLMSLLPLARFAVAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVVKDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQARWWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSESAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQCTTVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGANTRPDLDLRDPICDDFFQLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQVQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT
  
Inhibitor
Name:
BDBM87173
Synonyms:
N-[2-[4-(2-keto-3H-benzimidazol-1-yl)piperidino]ethyl]thiazole-4-carboxamide;2,2,2-trifluoroacetic acid | N-[2-[4-(2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1,3-thiazole-4-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid | N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-4-thiazolecarboxamide;2,2,2-trifluoroacetic acid | N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1,3-thiazole-4-carboxamide;2,2,2-trifluoroacetic acid | VU0366535-1 | cid_53469992
Type:
Small organic molecule
Emp. Form.:
C18H21N5O2S
Mol. Mass.:
371.457
SMILES:
O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cscn1
Structure:
Search PDB for entries with ligand similarity: