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Target
Phospholipase D2
Ligand
BDBM87170
Substrate
n/a
Meas. Tech.
PLD2 purified enzyme concentration response
IC50
28±n/a nM
Citation
 PubChem, PC PLD2 purified enzyme concentration response PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase D2
Synonyms:
PLD2 | PLD2_HUMAN | Phospholipase D2 | Phospholipase D2 (PLD2) | phospholipase D2 isoform PLD2A
Type:
Protein
Mol. Mass.:
106002.47
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
933
Sequence:
MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFAPGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVLMSLLPLARFAVAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVVKDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQARWWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSESAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQCTTVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGANTRPDLDLRDPICDDFFQLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQVQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT
  
Inhibitor
Name:
BDBM87170
Synonyms:
CHEMBL1254176 | N-[2-[1-(4-bromophenyl)-4-keto-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-5-fluoro-1H-indole-2-carboxamide;2,2,2-trifluoroacetic acid | N-[2-[1-(4-bromophenyl)-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-5-fluoranyl-1H-indole-2-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid | N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-5-fluoro-1H-indole-2-carboxamide;2,2,2-trifluoroacetic acid | VU0402728-1 | cid_46938540
Type:
Small organic molecule
Emp. Form.:
C24H25BrFN5O2
Mol. Mass.:
514.39
SMILES:
Fc1ccc2[nH]c(cc2c1)C(=O)NCCN1CCC2(CC1)N(CNC2=O)c1ccc(Br)cc1
Structure:
Search PDB for entries with ligand similarity: