Reaction Details Report a problem with these data
Target
High affinity choline transporter 1
Ligand
BDBM87578
Substrate
n/a
Meas. Tech.
JHICC_CHT_Inh_3H uptake_CRC
IC50
3761.879384±n/a nM
Citation
 PubChem, PC JHICC_CHT_Inh_3H uptake_CRC PubChem Bioassay (2012)[AID] 
Target
Name:
High affinity choline transporter 1
Synonyms:
CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1
Type:
PROTEIN
Mol. Mass.:
63194.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1464247
Residue:
580
Sequence:
MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFKTLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM87578
Synonyms:
MLS001101393 | N-(2-phenylethyl)-3-(1-propylpiperidin-4-yl)oxy-benzamide | N-(2-phenylethyl)-3-(1-propylpiperidin-4-yl)oxybenzamide | N-(2-phenylethyl)-3-[(1-propyl-4-piperidinyl)oxy]benzamide | N-phenethyl-3-[(1-propyl-4-piperidyl)oxy]benzamide | SMR000664527 | cid_24819334
Type:
Small organic molecule
Emp. Form.:
C23H30N2O2
Mol. Mass.:
366.4965
SMILES:
CCCN1CCC(CC1)Oc1cccc(c1)C(=O)NCCc1ccccc1
Structure:
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