Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM34677
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>89179±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM34677
Synonyms:
3-(4-methylbenzoyl)benzo[g][1]benzofuran-4,5-dione | 3-(4-methylbenzoyl)naphtho[1,2-b]furan-4,5-dione | 3-(4-methylphenyl)carbonylbenzo[g][1]benzofuran-4,5-dione | 3-[(4-methylphenyl)-oxomethyl]benzo[g]benzofuran-4,5-dione | 3-p-toluoylbenzo[g]benzofuran-4,5-quinone | MLS000532156 | SMR000137097 | cid_1736341
Type:
Small organic molecule
Emp. Form.:
C20H12O4
Mol. Mass.:
316.3069
SMILES:
Cc1ccc(cc1)C(=O)c1coc-2c1C(=O)C(=O)c1ccccc-21
Structure:
Search PDB for entries with ligand similarity: