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Target
Melanocortin receptor 4
Ligand
BDBM88432
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>89208±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88432
Synonyms:
(E)-1-[1-[2-(4-methylphenyl)-2-oxidanylidene-ethyl]benzimidazol-2-yl]-3-phenyl-prop-2-en-1-one | (E)-1-[1-[2-(4-methylphenyl)-2-oxoethyl]-2-benzimidazolyl]-3-phenyl-2-propen-1-one | (E)-1-[1-[2-(4-methylphenyl)-2-oxoethyl]benzimidazol-2-yl]-3-phenylprop-2-en-1-one | (E)-1-[1-[2-keto-2-(p-tolyl)ethyl]benzimidazol-2-yl]-3-phenyl-prop-2-en-1-one | 1-{1-[2-(4-methylphenyl)-2-oxoethyl]-1H-benzimidazol-2-yl}-3-phenyl-2-propen-1-one | MLS000545812 | SMR000163983 | cid_6260079
Type:
Small organic molecule
Emp. Form.:
C25H20N2O2
Mol. Mass.:
380.4385
SMILES:
Cc1ccc(cc1)C(=O)Cn1c(nc2ccccc12)C(=O)C=Cc1ccccc1 |w:21.23|
Structure:
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