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Target
Melanocortin receptor 4
Ligand
BDBM88435
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>89183±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88435
Synonyms:
1-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-4-(2-thienyl)-1H-pyrazol-5-amine | 2-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-4-thiophen-2-yl-pyrazol-3-amine | 2-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-4-thiophen-2-ylpyrazol-3-amine | 2-[4-(2,4-dichlorophenyl)-2-thiazolyl]-4-thiophen-2-yl-3-pyrazolamine | MLS000327653 | SMR000180601 | [2-[4-(2,4-dichlorophenyl)thiazol-2-yl]-4-(2-thienyl)pyrazol-3-yl]amine | cid_1474409
Type:
Small organic molecule
Emp. Form.:
C16H10Cl2N4S2
Mol. Mass.:
393.313
SMILES:
Nc1c(cnn1-c1nc(cs1)-c1ccc(Cl)cc1Cl)-c1cccs1
Structure:
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