Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM88437
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>89177±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88437
Synonyms:
Benzo[1,3]dioxole-5-carboxylic acid (5-benzothiazol-2-yl-2-chloro-phenyl)-amide | MLS000560266 | N-[5-(1,3-benzothiazol-2-yl)-2-chloranyl-phenyl]-1,3-benzodioxole-5-carboxamide | N-[5-(1,3-benzothiazol-2-yl)-2-chloro-phenyl]-piperonylamide | N-[5-(1,3-benzothiazol-2-yl)-2-chlorophenyl]-1,3-benzodioxole-5-carboxamide | SMR000178540 | cid_1090028
Type:
Small organic molecule
Emp. Form.:
C21H13ClN2O3S
Mol. Mass.:
408.858
SMILES:
Clc1ccc(cc1NC(=O)c1ccc2OCOc2c1)-c1nc2ccccc2s1
Structure:
Search PDB for entries with ligand similarity: