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Target
Melanocortin receptor 4
Ligand
BDBM88473
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>89278±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88473
Synonyms:
4-[4-[(2-chloranyl-6-fluoranyl-phenyl)methoxy]phenyl]pyrimidin-2-amine | 4-[4-[(2-chloro-6-fluorophenyl)methoxy]phenyl]-2-pyrimidinamine | 4-[4-[(2-chloro-6-fluorophenyl)methoxy]phenyl]pyrimidin-2-amine | 4-{4-[(2-chloro-6-fluorobenzyl)oxy]phenyl}-2-pyrimidinamine | MLS000721597 | SMR000335908 | [4-[4-(2-chloro-6-fluoro-benzyl)oxyphenyl]pyrimidin-2-yl]amine | cid_1472403
Type:
Small organic molecule
Emp. Form.:
C17H13ClFN3O
Mol. Mass.:
329.756
SMILES:
Nc1nccc(n1)-c1ccc(OCc2c(F)cccc2Cl)cc1
Structure:
Search PDB for entries with ligand similarity: