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Target
Melanocortin receptor 4
Ligand
BDBM88488
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>89186±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88488
Synonyms:
6-(3,4-dimethoxyphenyl)-9,10,10-triketo-N-[[5-methyl-2-(trifluoromethyl)-3-furyl]methyl]thioxanthene-1-carboxamide | 6-(3,4-dimethoxyphenyl)-N-[[5-methyl-2-(trifluoromethyl)-3-furanyl]methyl]-9,10,10-trioxo-1-thioxanthenecarboxamide | 6-(3,4-dimethoxyphenyl)-N-[[5-methyl-2-(trifluoromethyl)furan-3-yl]methyl]-9,10,10-trioxothioxanthene-1-carboxamide | 6-(3,4-dimethoxyphenyl)-N-[[5-methyl-2-(trifluoromethyl)furan-3-yl]methyl]-9,10,10-tris(oxidanylidene)thioxanthene-1-carboxamide | MLS001144825 | SMR000568214 | cid_44141945
Type:
Small organic molecule
Emp. Form.:
C29H22F3NO7S
Mol. Mass.:
585.548
SMILES:
COc1ccc(cc1OC)-c1ccc2C(=O)c3c(cccc3S(=O)(=O)c2c1)C(=O)NCc1cc(C)oc1C(F)(F)F
Structure:
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