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Target
Melanocortin receptor 4
Ligand
BDBM88511
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>89214±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88511
Synonyms:
MLS003124211 | N-[3-(3,4-dimethoxyphenyl)-6-(5-fluoranyl-2-methoxy-phenyl)imidazo[1,2-a]pyridin-8-yl]ethanamide | N-[3-(3,4-dimethoxyphenyl)-6-(5-fluoro-2-methoxy-phenyl)imidazo[1,2-a]pyridin-8-yl]acetamide | N-[3-(3,4-dimethoxyphenyl)-6-(5-fluoro-2-methoxyphenyl)-8-imidazo[1,2-a]pyridinyl]acetamide | N-[3-(3,4-dimethoxyphenyl)-6-(5-fluoro-2-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl]acetamide | SMR001292721 | cid_46943096
Type:
Small organic molecule
Emp. Form.:
C24H22FN3O4
Mol. Mass.:
435.4476
SMILES:
COc1ccc(cc1OC)-c1cnc2c(NC(C)=O)cc(cn12)-c1cc(F)ccc1OC
Structure:
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