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Target
Melanocortin receptor 4
Ligand
BDBM88518
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
12374±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88518
Synonyms:
MLS003124246 | N-[6-(3,4-dimethoxyphenyl)-3-[3-(trifluoromethyl)phenyl]-8-imidazo[1,2-a]pyridinyl]formamide | N-[6-(3,4-dimethoxyphenyl)-3-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-8-yl]formamide | N-[6-(3,4-dimethoxyphenyl)-3-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-8-yl]methanamide | SMR001292781 | cid_46944097
Type:
Small organic molecule
Emp. Form.:
C23H18F3N3O3
Mol. Mass.:
441.4025
SMILES:
COc1ccc(cc1OC)-c1cc(NC=O)c2ncc(-c3cccc(c3)C(F)(F)F)n2c1
Structure:
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