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Target
Delta-type opioid receptor
Ligand
BDBM59960
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92483±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM59960
Synonyms:
(3-nitrophenyl) 2-[2-oxidanylidene-2-[(4-propan-2-ylphenyl)amino]ethyl]sulfanylpyridine-3-carboxylate | (3-nitrophenyl) 2-[2-oxo-2-(4-propan-2-ylanilino)ethyl]sulfanylpyridine-3-carboxylate | 2-[(2-cumidino-2-keto-ethyl)thio]nicotinic acid (3-nitrophenyl) ester | 2-[[2-oxo-2-(4-propan-2-ylanilino)ethyl]thio]-3-pyridinecarboxylic acid (3-nitrophenyl) ester | 3-nitrophenyl 2-({2-[(4-isopropylphenyl)amino]-2-oxoethyl}thio)nicotinate | MLS000584020 | SMR000207006 | cid_4066820
Type:
Small organic molecule
Emp. Form.:
C23H21N3O5S
Mol. Mass.:
451.495
SMILES:
CC(C)c1ccc(NC(=O)CSc2ncccc2C(=O)Oc2cccc(c2)[N+]([O-])=O)cc1
Structure:
Search PDB for entries with ligand similarity: