Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM68044
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92479±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM68044
Synonyms:
1-(1-naphthalenyloxy)-3-[2-[4-(trifluoromethyl)phenyl]ethylamino]-2-propanol | 1-(1-naphthoxy)-3-[2-[4-(trifluoromethyl)phenyl]ethylamino]propan-2-ol | 1-naphthalen-1-yloxy-3-[2-[4-(trifluoromethyl)phenyl]ethylamino]propan-2-ol | MLS000334371 | SMR000249129 | cid_3605184
Type:
Small organic molecule
Emp. Form.:
C22H22F3NO2
Mol. Mass.:
389.4108
SMILES:
OC(CNCCc1ccc(cc1)C(F)(F)F)COc1cccc2ccccc12
Structure:
Search PDB for entries with ligand similarity: