Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM88464
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>64569±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88464
Synonyms:
(10Z)-10-[(4-hydroxyanilino)methylene]-8,8-dimethyl-pyrano[2,3-f]chromene-2,9-quinone | (10Z)-10-[(4-hydroxyanilino)methylidene]-8,8-dimethylpyrano[2,3-f][1]benzopyran-2,9-dione | (10Z)-10-[(4-hydroxyanilino)methylidene]-8,8-dimethylpyrano[2,3-f]chromene-2,9-dione | (10Z)-10-[[(4-hydroxyphenyl)amino]methylidene]-8,8-dimethyl-pyrano[2,3-f]chromene-2,9-dione | 10-{[(4-hydroxyphenyl)amino]methylene}-8,8-dimethyl-2H,8H-pyrano[2,3-f]chromene-2,9(10H)-dione | MLS000690659 | SMR000298918 | cid_2295134
Type:
Small organic molecule
Emp. Form.:
C21H17NO5
Mol. Mass.:
363.3634
SMILES:
CC1(C)Oc2ccc3ccc(=O)oc3c2C(=CNc2ccc(O)cc2)C1=O |w:16.18|
Structure:
Search PDB for entries with ligand similarity: