Target
Delta-type opioid receptor
Ligand
BDBM57887
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92494±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM57887
Synonyms:
3-((5Z)-5-{[1-(2,6-dimethylphenyl)-1H-pyrrol-2-yl]methylene}-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)benzoic acid | 3-[(5Z)-5-[[1-(2,6-dimethylphenyl)-2-pyrrolyl]methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]benzoic acid | 3-[(5Z)-5-[[1-(2,6-dimethylphenyl)pyrrol-2-yl]methylene]-4-keto-2-thioxo-thiazolidin-3-yl]benzoic acid | 3-[(5Z)-5-[[1-(2,6-dimethylphenyl)pyrrol-2-yl]methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid | 3-[(5Z)-5-[[1-(2,6-dimethylphenyl)pyrrol-2-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid | MLS000675293 | SMR000314015 | cid_16194382
Type:
Small organic molecule
Emp. Form.:
C23H18N2O3S2
Mol. Mass.:
434.531
SMILES:
Cc1cccc(C)c1-n1cccc1\C=C1/SC(=S)N(C1=O)c1cccc(c1)C(O)=O |(3.08,-1.79,;4.41,-2.56,;4.41,-4.1,;5.75,-4.87,;7.08,-4.1,;7.08,-2.56,;8.41,-1.79,;5.75,-1.79,;5.75,-.25,;4.5,.65,;4.98,2.12,;6.52,2.12,;6.99,.65,;8.46,.18,;9.6,1.21,;9.44,2.74,;10.85,3.37,;11.17,4.87,;11.88,2.22,;11.11,.89,;11.74,-.52,;13.41,2.38,;14.04,3.79,;15.57,3.95,;16.47,2.7,;15.85,1.3,;14.32,1.14,;16.75,.05,;18.28,.21,;16.13,-1.36,)|
Structure:
Search PDB for entries with ligand similarity: