Target
Delta-type opioid receptor
Ligand
BDBM88487
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92494±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88487
Synonyms:
(Z)-2-(5-methyl-1-tetrazolyl)-3-phenyl-2-propenoic acid [2-(4-chloro-2-fluoroanilino)-2-oxoethyl] ester | (Z)-2-(5-methyltetrazol-1-yl)-3-phenyl-acrylic acid [2-(4-chloro-2-fluoro-anilino)-2-keto-ethyl] ester | MLS001080259 | SMR000706997 | [2-(4-chloro-2-fluoroanilino)-2-oxoethyl] (Z)-2-(5-methyltetrazol-1-yl)-3-phenylprop-2-enoate | [2-[(4-chloranyl-2-fluoranyl-phenyl)amino]-2-oxidanylidene-ethyl] (Z)-2-(5-methyl-1,2,3,4-tetrazol-1-yl)-3-phenyl-prop-2-enoate | cid_18274125
Type:
Small organic molecule
Emp. Form.:
C19H15ClFN5O3
Mol. Mass.:
415.806
SMILES:
Cc1nnnn1\C(=C/c1ccccc1)C(=O)OCC(=O)Nc1ccc(Cl)cc1F
Structure:
Search PDB for entries with ligand similarity: