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Target
Delta-type opioid receptor
Ligand
BDBM88495
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92452±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88495
Synonyms:
MLS002724427 | N-(3,4-dimethylphenyl)-1-[3-[4-(2,4,6-trimethylbenzyl)piperazino]propyl]-1,2,4-triazole-3-carboxamide | N-(3,4-dimethylphenyl)-1-[3-[4-[(2,4,6-trimethylphenyl)methyl]-1-piperazinyl]propyl]-1,2,4-triazole-3-carboxamide | N-(3,4-dimethylphenyl)-1-[3-[4-[(2,4,6-trimethylphenyl)methyl]piperazin-1-yl]propyl]-1,2,4-triazole-3-carboxamide | SMR001595293 | cid_45281081
Type:
Small organic molecule
Emp. Form.:
C28H38N6O
Mol. Mass.:
474.6409
SMILES:
Cc1cc(C)c(CN2CCN(CCCn3cnc(n3)C(=O)Nc3ccc(C)c(C)c3)CC2)c(C)c1
Structure:
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