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Target
Delta-type opioid receptor
Ligand
BDBM88504
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>64588±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88504
Synonyms:
1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(6-methoxy-3-pyridinyl)-(2-methylphenyl)methyl]-4-piperidinecarboxamide | 1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(6-methoxy-3-pyridyl)-(o-tolyl)methyl]isonipecotamide | 1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(6-methoxypyridin-3-yl)-(2-methylphenyl)methyl]piperidine-4-carboxamide | 1-[2-[2,4-bis(chloranyl)phenoxy]ethyl]-N-[(6-methoxypyridin-3-yl)-(2-methylphenyl)methyl]piperidine-4-carboxamide | MLS003121753 | SMR001284950 | cid_46942448
Type:
Small organic molecule
Emp. Form.:
C28H31Cl2N3O3
Mol. Mass.:
528.47
SMILES:
COc1ccc(cn1)C(NC(=O)C1CCN(CCOc2ccc(Cl)cc2Cl)CC1)c1ccccc1C
Structure:
Search PDB for entries with ligand similarity: