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Target
Melanocortin receptor 4
Ligand
BDBM88570
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64551±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88570
Synonyms:
2-[[5-[4-(tosylamino)phenyl]-1,3,4-oxadiazol-2-yl]thio]acetic acid ethyl ester | 2-[[5-[4-[(4-methylphenyl)sulfonylamino]phenyl]-1,3,4-oxadiazol-2-yl]thio]acetic acid ethyl ester | MLS000072972 | SMR000002544 | cid_654288 | ethyl 2-[[5-[4-[(4-methylphenyl)sulfonylamino]phenyl]-1,3,4-oxadiazol-2-yl]sulfanyl]acetate | ethyl 2-[[5-[4-[(4-methylphenyl)sulfonylamino]phenyl]-1,3,4-oxadiazol-2-yl]sulfanyl]ethanoate | {5-[4-(Toluene-4-sulfonylamino)-phenyl]-[1,3,4]oxadiazol-2-ylsulfanyl}-acetic acid ethyl ester
Type:
Small organic molecule
Emp. Form.:
C19H19N3O5S2
Mol. Mass.:
433.501
SMILES:
CCOC(=O)CSc1nnc(o1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1
Structure:
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