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Target
Melanocortin receptor 4
Ligand
BDBM88576
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
10869±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88576
Synonyms:
3-(1-benzylbenzimidazol-2-yl)sulfanyloxolan-2-one | 3-[(1-benzyl-1H-benzimidazol-2-yl)thio]dihydro-2(3H)-furanone | 3-[(1-benzylbenzimidazol-2-yl)thio]tetrahydrofuran-2-one | 3-[1-(phenylmethyl)benzimidazol-2-yl]sulfanyloxolan-2-one | 3-[[1-(phenylmethyl)-2-benzimidazolyl]thio]-2-oxolanone | MLS000063362 | SMR000075066 | cid_2948635
Type:
Small organic molecule
Emp. Form.:
C18H16N2O2S
Mol. Mass.:
324.397
SMILES:
O=C1OCCC1Sc1nc2ccccc2n1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: