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Target
Melanocortin receptor 4
Ligand
BDBM57188
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64590±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM57188
Synonyms:
5-(4-Bromo-3,5-dimethyl-pyrazole-1-sulfonyl)-2,4-dichloro-benzoic acid methyl ester | 5-(4-bromo-3,5-dimethyl-pyrazol-1-yl)sulfonyl-2,4-dichloro-benzoic acid methyl ester | 5-[(4-bromo-3,5-dimethyl-1-pyrazolyl)sulfonyl]-2,4-dichlorobenzoic acid methyl ester | MLS000552104 | SMR000145828 | cid_1895567 | methyl 5-(4-bromanyl-3,5-dimethyl-pyrazol-1-yl)sulfonyl-2,4-bis(chloranyl)benzoate | methyl 5-(4-bromo-3,5-dimethylpyrazol-1-yl)sulfonyl-2,4-dichlorobenzoate
Type:
Small organic molecule
Emp. Form.:
C13H11BrCl2N2O4S
Mol. Mass.:
442.112
SMILES:
COC(=O)c1cc(c(Cl)cc1Cl)S(=O)(=O)n1nc(C)c(Br)c1C
Structure:
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