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Target
Melanocortin receptor 4
Ligand
BDBM61464
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64575±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM61464
Synonyms:
3-chloranyl-N-[3-[(3-chloranyl-4-nitro-phenyl)carbonylamino]-2,2-dimethyl-propyl]-4-nitro-benzamide | 3-chloro-N-[3-({3-chloro-4-nitrobenzoyl}amino)-2,2-dimethylpropyl]-4-nitrobenzamide | 3-chloro-N-[3-[(3-chloro-4-nitro-benzoyl)amino]-2,2-dimethyl-propyl]-4-nitro-benzamide | 3-chloro-N-[3-[(3-chloro-4-nitrobenzoyl)amino]-2,2-dimethylpropyl]-4-nitrobenzamide | 3-chloro-N-[3-[[(3-chloro-4-nitrophenyl)-oxomethyl]amino]-2,2-dimethylpropyl]-4-nitrobenzamide | MLS000545868 | SMR000159469 | cid_1746062
Type:
Small organic molecule
Emp. Form.:
C19H18Cl2N4O6
Mol. Mass.:
469.275
SMILES:
CC(C)(CNC(=O)c1ccc(c(Cl)c1)[N+]([O-])=O)CNC(=O)c1ccc(c(Cl)c1)[N+]([O-])=O
Structure:
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