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Target
Melanocortin receptor 4
Ligand
BDBM88595
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64578±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88595
Synonyms:
4-(3,5-dichlorophenyl)-3-(2-quinolinyl)-1H-1,2,4-triazole-5-thione | 4-(3,5-dichlorophenyl)-3-(2-quinolyl)-1H-1,2,4-triazole-5-thione | 4-(3,5-dichlorophenyl)-3-quinolin-2-yl-1H-1,2,4-triazole-5-thione | 4-(3,5-dichlorophenyl)-5-(2-quinolinyl)-4H-1,2,4-triazole-3-thiol | 4-[3,5-bis(chloranyl)phenyl]-3-quinolin-2-yl-1H-1,2,4-triazole-5-thione | MLS000582745 | SMR000201448 | cid_1256628
Type:
Small organic molecule
Emp. Form.:
C17H10Cl2N4S
Mol. Mass.:
373.259
SMILES:
Clc1cc(Cl)cc(c1)-n1c(n[nH]c1=S)-c1ccc2ccccc2n1
Structure:
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