Target
Melanocortin receptor 4
Ligand
BDBM88607
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64583±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88607
Synonyms:
2-[4-[methyl(2-thienylsulfonyl)amino]phenoxy]acetic acid [2-(4-bromoanilino)-2-keto-ethyl] ester | 2-[4-[methyl(thiophen-2-ylsulfonyl)amino]phenoxy]acetic acid [2-(4-bromoanilino)-2-oxoethyl] ester | MLS000416520 | SMR000243419 | [2-(4-bromoanilino)-2-oxoethyl] 2-[4-[methyl(thiophen-2-ylsulfonyl)amino]phenoxy]acetate | [2-[(4-bromophenyl)amino]-2-oxidanylidene-ethyl] 2-[4-[methyl(thiophen-2-ylsulfonyl)amino]phenoxy]ethanoate | cid_2577649
Type:
Small organic molecule
Emp. Form.:
C21H19BrN2O6S2
Mol. Mass.:
539.419
SMILES:
CN(c1ccc(OCC(=O)OCC(=O)Nc2ccc(Br)cc2)cc1)S(=O)(=O)c1cccs1
Structure:
Search PDB for entries with ligand similarity: