Target
Melanocortin receptor 4
Ligand
BDBM88609
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64575±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88609
Synonyms:
2-(tosylamino)acetic acid [2-keto-2-[(2-methoxydibenzofuran-3-yl)amino]ethyl] ester | 2-[(4-methylphenyl)sulfonylamino]acetic acid [2-[(2-methoxy-3-dibenzofuranyl)amino]-2-oxoethyl] ester | MLS000393389 | SMR000243858 | [2-[(2-methoxydibenzofuran-3-yl)amino]-2-oxidanylidene-ethyl] 2-[(4-methylphenyl)sulfonylamino]ethanoate | [2-[(2-methoxydibenzofuran-3-yl)amino]-2-oxoethyl] 2-[(4-methylphenyl)sulfonylamino]acetate | cid_2078942
Type:
Small organic molecule
Emp. Form.:
C24H22N2O7S
Mol. Mass.:
482.506
SMILES:
COc1cc2c(cc1NC(=O)COC(=O)CNS(=O)(=O)c1ccc(C)cc1)oc1ccccc21
Structure:
Search PDB for entries with ligand similarity: