Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM88618
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64581±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88618
Synonyms:
1-methyl-4-[2-[4-(trifluoromethyl)phenyl]sulfanylphenoxy]piperidine;oxalic acid | 1-methyl-4-[2-[[4-(trifluoromethyl)phenyl]thio]phenoxy]piperidine;oxalic acid | 1-methyl-4-piperidinyl 2-{[4-(trifluoromethyl)phenyl]sulfanyl}phenyl ether | MLS000703854 | SMR000224863 | cid_14400561 | ethanedioic acid;1-methyl-4-[2-[4-(trifluoromethyl)phenyl]sulfanylphenoxy]piperidine
Type:
Small organic molecule
Emp. Form.:
C19H20F3NOS
Mol. Mass.:
367.428
SMILES:
CN1CCC(CC1)Oc1ccccc1Sc1ccc(cc1)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: