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Target
Melanocortin receptor 4
Ligand
BDBM88619
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64541±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88619
Synonyms:
4-[3-(4-methoxyphenyl)-3-oxopropyl]-1-piperazinecarboxylic acid ethyl ester;hydrochloride | 4-[3-keto-3-(4-methoxyphenyl)propyl]piperazine-1-carboxylic acid ethyl ester;hydrochloride | MLS000727731 | SMR000306428 | cid_16188016 | ethyl 4-[3-(4-methoxyphenyl)-3-oxidanylidene-propyl]piperazine-1-carboxylate;hydrochloride | ethyl 4-[3-(4-methoxyphenyl)-3-oxopropyl]piperazine-1-carboxylate;hydrochloride
Type:
Small organic molecule
Emp. Form.:
C17H24N2O4
Mol. Mass.:
320.3835
SMILES:
CCOC(=O)N1CCN(CCC(=O)c2ccc(OC)cc2)CC1
Structure:
Search PDB for entries with ligand similarity: