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Target
Melanocortin receptor 4
Ligand
BDBM63476
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64573±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM63476
Synonyms:
2-[(2,3-dimethoxybenzoyl)amino]-5-isopropyl-3-thiophenecarboxamide | 2-[(2,3-dimethoxybenzoyl)amino]-5-propan-2-ylthiophene-3-carboxamide | 2-[(2,3-dimethoxyphenyl)carbonylamino]-5-propan-2-yl-thiophene-3-carboxamide | 2-[[(2,3-dimethoxyphenyl)-oxomethyl]amino]-5-propan-2-yl-3-thiophenecarboxamide | 5-isopropyl-2-(o-veratroylamino)thiophene-3-carboxamide | MLS000684170 | SMR000295841 | cid_1245133
Type:
Small organic molecule
Emp. Form.:
C17H20N2O4S
Mol. Mass.:
348.417
SMILES:
COc1cccc(C(=O)Nc2sc(cc2C(N)=O)C(C)C)c1OC
Structure:
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