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Target
Melanocortin receptor 4
Ligand
BDBM88640
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64587±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88640
Synonyms:
MLS000760665 | N-[5-(diethylsulfamoyl)-2-(4-morpholinyl)phenyl]-2-fluorobenzamide | N-[5-(diethylsulfamoyl)-2-morpholin-4-yl-phenyl]-2-fluoranyl-benzamide | N-[5-(diethylsulfamoyl)-2-morpholin-4-ylphenyl]-2-fluorobenzamide | N-[5-(diethylsulfamoyl)-2-morpholino-phenyl]-2-fluoro-benzamide | SMR000370585 | cid_16196854
Type:
Small organic molecule
Emp. Form.:
C21H26FN3O4S
Mol. Mass.:
435.512
SMILES:
CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2ccccc2F)c1
Structure:
Search PDB for entries with ligand similarity: