Reaction Details Report a problem with these data
Target
V-type proton ATPase subunit c'
Ligand
BDBM88691
Substrate
n/a
Meas. Tech.
Dose Response with BCECF Assay for V-ATPase inhibitors that increase vacuolar pH, Powder Set 1
EC50
728±n/a nM
Citation
 PubChem, PC Dose Response with BCECF Assay for V-ATPase inhibitors that increase vacuolar pH, Powder Set 1 PubChem Bioassay (2012)[AID] 
Target
Name:
V-type proton ATPase subunit c'
Synonyms:
CLS9 | TFP3 | VATL2_YEAST | VMA11 | Vma11p
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17039.28
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_6325022
Residue:
164
Sequence:
MSTQLASNIYAPLYAPFFGFAGCAAAMVLSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGMVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTRGSE
  
Inhibitor
Name:
BDBM88691
Synonyms:
VU0465039-1 | [4-(6-methoxy-1,3-benzothiazol-2-yl)-1-piperazinyl]-(5-nitro-2-furanyl)methanone | [4-(6-methoxy-1,3-benzothiazol-2-yl)piperazin-1-yl]-(5-nitrofuran-2-yl)methanone | [4-(6-methoxy-1,3-benzothiazol-2-yl)piperazino]-(5-nitro-2-furyl)methanone | cid_7538979
Type:
Small organic molecule
Emp. Form.:
C17H16N4O5S
Mol. Mass.:
388.398
SMILES:
COc1ccc2nc(sc2c1)N1CCN(CC1)C(=O)c1ccc(o1)[N+]([O-])=O
Structure:
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