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Target
Tyrosine-protein phosphatase non-receptor type 5
Ligand
BDBM61162
Substrate
n/a
Meas. Tech.
Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay
IC50
27500±n/a nM
Citation
 PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 5
Synonyms:
PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
63510.68
Organism:
Homo sapiens (Human)
Description:
gi_90652859
Residue:
565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
  
Inhibitor
Name:
BDBM61162
Synonyms:
3-(6-hydroxy-2-keto-chromen-3-yl)-1-phenyl-pyrazole-4-carbaldehyde | 3-(6-hydroxy-2-oxo-1-benzopyran-3-yl)-1-phenyl-4-pyrazolecarboxaldehyde | 3-(6-hydroxy-2-oxochromen-3-yl)-1-phenylpyrazole-4-carbaldehyde | 3-(6-oxidanyl-2-oxidanylidene-chromen-3-yl)-1-phenyl-pyrazole-4-carbaldehyde | MLS000565419 | SMR000152596 | cid_2319222
Type:
Small organic molecule
Emp. Form.:
C19H12N2O4
Mol. Mass.:
332.3096
SMILES:
Oc1ccc2oc(=O)c(cc2c1)-c1nn(cc1C=O)-c1ccccc1
Structure:
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