Target
Tyrosine-protein phosphatase non-receptor type 5
Ligand
BDBM88796
Substrate
n/a
Meas. Tech.
Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay
IC50
17200±n/a nM
Citation
 PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 5
Synonyms:
PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
63510.68
Organism:
Homo sapiens (Human)
Description:
gi_90652859
Residue:
565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
  
Inhibitor
Name:
BDBM88796
Synonyms:
MLS001110505 | N-(2-chloranyl-4-methyl-phenyl)-2-morpholin-4-yl-1,3-benzothiazole-6-carboxamide | N-(2-chloro-4-methyl-phenyl)-2-morpholino-1,3-benzothiazole-6-carboxamide | N-(2-chloro-4-methylphenyl)-2-(4-morpholinyl)-1,3-benzothiazole-6-carboxamide | N-(2-chloro-4-methylphenyl)-2-morpholin-4-yl-1,3-benzothiazole-6-carboxamide | SMR000624920 | cid_24793673
Type:
Small organic molecule
Emp. Form.:
C19H18ClN3O2S
Mol. Mass.:
387.883
SMILES:
Cc1ccc(NC(=O)c2ccc3nc(sc3c2)N2CCOCC2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: