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Target
Tyrosine-protein phosphatase non-receptor type 5
Ligand
BDBM76022
Substrate
n/a
Meas. Tech.
Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay
IC50
18000±n/a nM
Citation
 PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 5
Synonyms:
PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
63510.68
Organism:
Homo sapiens (Human)
Description:
gi_90652859
Residue:
565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
  
Inhibitor
Name:
BDBM76022
Synonyms:
5-bromanyl-N-[4-(6-methoxypyridazin-3-yl)phenyl]furan-2-carboxamide | 5-bromo-N-[4-(6-methoxy-3-pyridazinyl)phenyl]-2-furancarboxamide | 5-bromo-N-[4-(6-methoxypyridazin-3-yl)phenyl]-2-furamide | 5-bromo-N-[4-(6-methoxypyridazin-3-yl)phenyl]furan-2-carboxamide | MLS001236653 | SMR000812782 | cid_7593595
Type:
Small organic molecule
Emp. Form.:
C16H12BrN3O3
Mol. Mass.:
374.189
SMILES:
COc1ccc(nn1)-c1ccc(NC(=O)c2ccc(Br)o2)cc1
Structure:
Search PDB for entries with ligand similarity: