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Target
Dual specificity protein phosphatase 3
Ligand
BDBM81020
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
810±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM81020
Synonyms:
(3,4-dichlorophenyl)-(4-ethyl-1-piperazinyl)methanethione | (3,4-dichlorophenyl)-(4-ethylpiperazin-1-yl)methanethione | (3,4-dichlorophenyl)-(4-ethylpiperazino)methanethione | 1-[(3,4-dichlorophenyl)carbonothioyl]-4-ethylpiperazine | MLS000594177 | SMR000143195 | cid_848275
Type:
Small organic molecule
Emp. Form.:
C13H16Cl2N2S
Mol. Mass.:
303.251
SMILES:
CCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1
Structure:
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