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Target
Dual specificity protein phosphatase 3
Ligand
BDBM88726
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
1620±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM88726
Synonyms:
MLS000572016 | N-(1,3-benzothiazol-2-yl)-2-(3-methoxyphenyl)-4-quinolinecarboxamide | N-(1,3-benzothiazol-2-yl)-2-(3-methoxyphenyl)cinchoninamide | N-(1,3-benzothiazol-2-yl)-2-(3-methoxyphenyl)quinoline-4-carboxamide | N-1,3-benzothiazol-2-yl-2-(3-methoxyphenyl)-4-quinolinecarboxamide | SMR000194176 | cid_1221629
Type:
Small organic molecule
Emp. Form.:
C24H17N3O2S
Mol. Mass.:
411.476
SMILES:
COc1cccc(c1)-c1cc(C(=O)Nc2nc3ccccc3s2)c2ccccc2n1
Structure:
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