Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM48788
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
24100±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM48788
Synonyms:
MLS000663768 | N-(N'-piperonylamidino)benzamide | N-[N'-(1,3-benzodioxol-5-ylmethyl)carbamimidoyl]benzamide | N-[[(1,3-benzodioxol-5-ylmethyl)amino](imino)methyl]benzamide | N-[amino(1,3-benzodioxol-5-ylmethylimino)methyl]benzamide | SMR000293067 | cid_2945670
Type:
Small organic molecule
Emp. Form.:
C16H15N3O3
Mol. Mass.:
297.3086
SMILES:
NC(NC(=O)c1ccccc1)=NCc1ccc2OCOc2c1 |w:11.12|
Structure:
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